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Order ID 200432
Provider Example Provider MD
Specimen
Collected
09/29/2021
Received
09/30/2021
Test order
Created
10/01/2021
Reported
10/02/2021
Patient
Smith,
Mary L
Gender - DOB
Female - 53 years old
Identifier Received
Exagen ID
300955
AVISE® CTD Test Report

AVISE® Lupus Result : Negative – Index: -5.0

A result is marked as equivocal when one or more critical values is close to a threshold that would significantly change the index value if the threshold was crossed.

The output of the AVISE® Lupus out put algorythem:
Tier 1 index helps identify patients that have highly
elevated or positive SLE associated analytes



Expanded Reference Ranges View
< 15 -Negative | 15-75 -Positive | > 75 -Strong Positive
< 61 -Negative | 61-200 -Positive | > 200 -Strong Positive
≤ 200 -Negative | 201-301 -Equivocal | ≥ 302 -Positive
< 5 -Negative | 5-10 -Equivocal | > 10 -Positive
< 20 -Negative | 20-59 -Positive | ≥ 60 -Strong Positive
< 7 -Negative | 7-10 -Equivocal | > 10 -Positive
< 7 -Negative | 7-10 -Equivocal | > 10 -Positive
< 7 -Negative | 7-10 -Equivocal | > 10 -Positive
< 7 -Negative | 7-10 -Equivocal | > 10 -Positive
< 7 -Negative | 7-10 -Equivocal | > 10 -Positive
 
 
 
 

Clear All

CB-CAP EC4d
CB-CAP BC4d
Anti-dsDNA
(Confirmed by Crithidia)
"Is anti-dsDNA confirmed
positive by crithidia?"
Yes No
Anti-SM
ANA
Anti-SS-B-La
Anti-Scl-70
Anti-CENP
Anti-Jo-1
Anti-CCP

Tier 1 Analytes: 4 analytes that are associated with first
step of the AVISE® Lupus analysis. Associated with
SLE with a high degree ofspecificity

A tier 1 positive is triggered if:

  • Anti-Sm is > 10 U/mL
  • EC4d is > 75 Net MFI
  • BC4d is > 200 Net MFI
  • Anti-dsDNA is > 301 U/ml and is also
    confirmed by Crithidia
  Negative
 Low Positive
 Strong Positive
 Equivocal
 
Detailed Equation View

-5.2954 + ANA Comp# + [  EC4d Comp# + BC4d Comp#  ] + (  Specificity Comp#  ) = 0
-5.2954 + 0.9771 x 0 +[0.3053x Ln ( 1 ) + 1.0278 x Ln ( 1 )] + - 2.4944 x 0 = 0
Reference:
Putterman C, et al. Lupus Science & Medicine. 2014.
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