AVISE SLE Monitor

AVISE SLE Monitor is a unique combination of 6 specialized biomarkers including EC4d and PC4d, to help assess patients with SLE.

This specialized SLE disease monitoring test is clinically proven to correlate with SLE disease activity.

Clinical Utility: AVISE SLE Monitor Test Report

The AVISE SLE Monitor test should be considered any time the condition of a SLE patient is being assessed.

If the patient is also being monitored with AVISE® HCQ, the AVISE SLE Monitor test report will also include an AVISE HCQ test result page.

References:

1. Kao A, Navratil J, Ruffing M, et al. Erythocyte C3d and C4d for Monitoring Disease Activity in Systemic Lupus Erythematosus. Arthritis & Rheumatism. 2010.
2. Buyon J, et al. Reduction in EC4d and anti-C1q antibodies associate with clinical improvement in SLE. Lupus Science and Medicine. 2016.
3. Merrill J, et al. Erythrocyte-bound C4d in combination with complement and autoantibody status for the monitoring of SLE. Lupus Science and Medicine. 2018.
4. Mahler M, Bentow C, O’Malley T, et al. Performance Characteristics of Different Anti-Double-Stranded DNA Antibody Assays in the Monitoring of Systemic Lupus Erythematosus. J Immunol Res. 2017;2017:1720902.
5. Petri M, Conklin J, Apilado R, et al. Complement C4d Split Products in Combination with Lupus Anticoagulant and Low Complement Associate with Thrombosis in SLE [abstract]. Arthritis Rheumatol. 2018
6. Kao A, McBurney C, Sattar A, et al. Relation of platelet C4d with all-cause mortality and ischemic stroke in patients with systemic lupus erythematosus. Transl Stroke Res 2014; 5(4):510-518.
7. Akhter E, Burlingame R, Seaman A, et al. Anti-C1Q antibodies have a higher correlation with flares of lupus nephritis than other serum markers. Lupus. 2012.
8. Data on file Exagen, Inc. 2018.