AVISE SLE Monitor
AVISE SLE Monitor is a unique combination of 6 specialized biomarkers including EC4d and PC4d, to help assess patients with SLE.
Biomarkers associated with SLE disease activity:
Biomarkers associated with adverse events in SLE:
Clinical Utility: AVISE SLE Monitor Test Report
The AVISE SLE Monitor test should be considered any time the condition of a SLE patient is being assessed.
If the patient is also being monitored with AVISE® HCQ, the AVISE SLE Monitor test report will also include an AVISE HCQ test result page.
- Kao A, Navratil J, Ruffing M, et al. Erythocyte C3d and C4d for Monitoring Disease Activity in Systemic Lupus Erythematosus. Arthritis & Rheumatism. 2010.
- Buyon J, et al. Reduction in EC4d and anti-C1q antibodies associate with clinical improvement in SLE. Lupus Science and Medicine. 2016.
- Merrill J, et al. Erythrocyte-bound C4d in combination with complement and autoantibody status for the monitoring of SLE. Lupus Science and Medicine. 2018.
- Mahler M, Bentow C, O’Malley T, et al. Performance Characteristics of Different Anti-Double-Stranded DNA Antibody Assays in the Monitoring of Systemic Lupus Erythematosus. J Immunol Res. 2017;2017:1720902.
- Petri M, Conklin J, Apilado R, et al. Complement C4d Split Products in Combination with Lupus Anticoagulant and Low Complement Associate with Thrombosis in SLE [abstract]. Arthritis Rheumatol. 2018
- Kao A, McBurney C, Sattar A, et al. Relation of platelet C4d with all-cause mortality and ischemic stroke in patients with systemic lupus erythematosus. Transl Stroke Res 2014; 5(4):510-518.
- Akhter E, Burlingame R, Seaman A, et al. Anti-C1Q antibodies have a higher correlation with flares of lupus nephritis than other serum markers. Lupus. 2012.
- Data on file Exagen, Inc. 2018.
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